Author

P. Giannakakou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Berger· 1 shared C. C. Au· 1 shared D. M. Nanus· 1 shared D. S. Rickman· 1 shared D. Sackett· 1 shared D. Worroll· 1 shared E. Mukhtar· 1 shared E. V. Navarro· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Berger

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Author profile →

2 papers

Recent·Most cited

AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in Castrate-Resistant Prostate Cancer

S. Kim, M. A. B. Jamalruddin, C. C. Au, E. Mukhtar, L. Portella, A. Berger, D. Worroll, D. S. Rickman, D. M. Nanus, P. Giannakakou

This study identifies unique nuclear import and chromatin engagement mechanisms of AR-V7 in castrate-resistant prostate cancer, suggesting a Hit-and-Run transcriptional mode.

bioRxiv · Jun 3, 2021Cancer Biology

Imatinib overrides taxane resistance by selective inhibition of novel CLIP1 variant obstructing the microtubule pore

K. Kita, P. V. Thakkar, G. Galletti, N. Madhukar, E. V. Navarro, I. Barasoain, H. V. Goodson, D. Sackett, J. F. Diaz, O. Elemento, M. A. Shah, P. Giannakakou

The paper identifies a novel CLIP-170 variant, CLIP-170S, that causes taxane resistance in gastric cancer and shows imatinib can reverse this resistance by selectively inhibiting CLIP-170S.

bioRxiv · Nov 11, 2019 · PreprintCancer Biology