P. H. von Hippel

This paper introduces a single-molecule fluorescence method to measure DNA breathing dynamics using (iCy3)2 dimer probes, revealing four conformational macrostates in DNA fork constructs.

The paper uses transition density models to analyze optical spectra of (iCy3)2 dimer probes, determining DNA conformational parameters near protein binding sites.

This study uses 2D fluorescence spectroscopy to analyze temperature-dependent conformational changes in ss-dsDNA junctions labeled with cyanine dimer probes, revealing position-dependent structural disorder.

This paper uses smFRET to study sub-millisecond conformational transitions in short ssDNA lattices, revealing three macrostates with distinct end-to-end distances.

The paper studies DNA breathing mechanisms at the dinucleotide level using simulations and experiments, identifying two chiral conformations and the role of ions and water.