Author

P. Holdship

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

P. J. Ratcliffe· 1 shared T. P. Keeley· 1 shared T. Q. To· 1 shared Y.-M. Tian· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

P. J. Ratcliffe

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1 paper

Recent·Most cited

Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen sensing pathways in mammalian cells

Y.-M. Tian, P. Holdship, T. Q. To, P. J. Ratcliffe, T. P. Keeley

This study compares the oxygen-sensing mechanisms of ADO and PHD enzymes, finding they regulate substrate stability with similar O2-sensitivity but differ in metal sensitivity and hypoxic feedback.

bioRxiv · Jun 25, 2023Cell Biology