Author

P. K. Purohit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Neelakantan· 2 shared S. Pasha· 2 shared A. Gopinath· 1 shared K. Tokatlidis· 1 shared N. Saini· 1 shared R. Edwards· 1 shared X. Liao· 1 shared

Activity by Year

2018-2020 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 5 mutual co-author links

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2 shared papersBioengineering

S. Neelakantan

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4 papers

Recent·Most cited

Extensions of the worm-like-chain model to tethered active filaments under tension

X. Liao, P. K. Purohit, A. Gopinath

The paper extends the worm-like-chain model to analyze tethered active filaments under tension, deriving force-extension relationships and mean square deflections under different boundary conditions.

bioRxiv · Jul 26, 2020Biophysics

A reduced order model of the spine to study pediatric scoliosis

S. Neelakantan, P. K. Purohit, S. Pasha

The paper uses an elastic rod model to simulate spinal deformations and identifies deformation patterns linked to clinical scoliosis curves.

bioRxiv · Apr 20, 2020Bioengineering

A semi-analytic elastic rod model of pediatric spinal deformity

S. Neelakantan, P. K. Purohit, S. Pasha

This study uses an elastic rod model to analyze spinal deformity in children, showing that pre-scoliotic sagittal curvature affects 3D loading leading to scoliosis.

bioRxiv · Apr 20, 2020Bioengineering

MiR-195 regulates mitochondrial function by targeting mitofusin-2 in breast cancer cells

P. K. Purohit, R. Edwards, K. Tokatlidis, N. Saini

This study shows miR-195 regulates mitochondrial function by targeting mitofusin-2, leading to mitochondrial fission and altered oxidative stress in breast cancer cells.

bioRxiv · Nov 22, 2018Cancer Biology