P. K. Raval

Performance of localization prediction algorithms decreases rapidly with the evolutionary distance to the training set increasing

The paper evaluates localization prediction algorithms across evolutionary distances and finds performance drops significantly, especially for plant mitochondria.

A molecular atlas of plastid and mitochondrial evolution from algae to angiosperms

The paper analyzes proteome and genome data to trace evolutionary changes in plastid and mitochondrial biology across eukaryotes, identifying unique protein families and molecular adaptations linked to major evolutionary transitions.

The layered costs and benefits of translational redundancy

This study manipulates redundancy in translation components of E. coli and finds nutrient-dependent fitness costs and benefits, revealing a layered hierarchy of redundancy organization.

Loss of plastid developmental genes coincides with a reversion to monoplastidy in hornworts

The paper identifies the loss of ARC3 and FtsZ2 genes in hornworts as the cause of their monoplastidic phenotype through genomic and transcriptomic analysis.

THE IMPACT OF MISTRANSLATION ON PHENOTYPIC VARIABILITY AND FITNESS

This study shows mistranslation increases phenotypic variation in E. coli cells but not across replicate populations, and provides a survival benefit under stress.

Global mistranslation facilitates sampling of beneficial mutations under stress

The paper shows that global mistranslation increases E. coli survival under DNA damage and high temperature by enhancing the SOS response and stress resistance through Lon protease.