Author

P. Koeffler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

B. C. Han· 1 shared C. Y. Goh· 1 shared D. Kappei· 1 shared G. Rane· 1 shared L. Xu· 1 shared L.-W. Deng· 1 shared M. Jeitany· 1 shared N. Zaal Anuar· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

B. C. Han

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2 papers

Recent·Most cited

ChIP-MS reveals the local chromatin composition by label-free quantitative proteomics

W. K. Yong, G. Rane, N. Zaal Anuar, X. Shao, C. Y. Goh, V. Khanchandani, V. L. S. Kuan, M. Jeitany, P. Koeffler, L.-W. Deng, T. Sanda, D. Kappei

The paper introduces ChIP-MS, a method combining ChIP with label-free quantitative mass spectrometry to analyze local chromatin composition, demonstrating its application at telomeres, with transcription factors, in tissue, and via dCas9-driven enrichment.

bioRxiv · Jan 27, 2023Biochemistry

Multiple Myeloma: Combination Therapy of BET Proteolysis Targeting Chimeric Molecule with CDK9 Inhibitor

S. L. Lim, P. Koeffler, L. Xu, B. C. Han, P. Shyamsunder, W. J. Chng

This study shows that combining a BET PROTAC (ARV 825) with a CDK9 inhibitor (AZD 4573) effectively reduces multiple myeloma cell viability and induces apoptosis.

bioRxiv · Apr 8, 2020Cancer Biology