Author

P. L. Chan

University of Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Organism:fungi (other)· 1

Frequent Co-Authors

Daisy Harris-Bosancic· 1 shared David A.J. LeckyiD· 1 shared Erin Clipston· 1 shared H. S. Kwan· 1 shared J. Chang· 1 shared J. Chiou· 1 shared Kazuyoshi Kawakami· 1 shared L. George· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Daisy Harris-Bosancic

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2 papers

Recent·Most cited

Organ-specific immune responses are strain-dependent in a mouse model of Cryptococcus neoformans brain infection

Man Shun Fu, L. George, Daisy Harris-Bosancic, Tahrim Hussain, Erin Clipston, P. L. Chan, Lozan Sheriff, David A.J. Lecky, Kazuyoshi Kawakami, Rebecca A. Drummond

This study examines how different Cryptococcus neoformans strains affect organ-specific immune responses in a mouse model of cryptococcal meningitis, finding strain-dependent effects independent of virulence.

Microbiology Spectrum · Feb 2, 2026Peer-reviewedImmunology

The Phylotranscriptomic Hourglass Pattern in Fungi: An Updated Model

Y. Xie, H. S. Kwan, P. L. Chan, W. Wu, J. Chiou, J. Chang

The paper updates the developmental hourglass model in fungi, identifying germinating spores as the conserved 'waist' and highlighting transcriptomic conservation across fungal phyla.

bioRxiv · Jul 14, 2022 · PreprintEvolutionary Biology