Author

P. Lynne Howell

Primary ORCID profile (0000-0002-2776-062X · 6 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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P. Lynne HowelliD6 papers · University of Toronto

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Brendan D Snarr· 1 shared Daniel J Wozniak· 1 shared Donald C Sheppard· 1 shared John Tam· 1 shared Laura K Jennings· 1 shared Mark J Lee· 1 shared Mathew J Pestrak· 1 shared Matthew R Parsek· 1 shared

Activity by Year

2015-2015 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Brendan D Snarr

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1 paper

Recent·Most cited

Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

Perrin Baker, Preston J HIll, Brendan D Snarr, Noor Alnabelseya, Mathew J Pestrak, Mark J Lee, Laura K Jennings, John Tam, Roman Melnyk, Matthew R Parsek, Donald C Sheppard, Daniel J Wozniak, P. Lynne Howell

This study demonstrates that glycoside hydrolases PelAh and PslGh can disrupt and prevent Pseudomonas aeruginosa biofilms by degrading exopolysaccharides, enhancing antibiotic efficacy, and improving immune response.

bioRxiv · Nov 26, 2015Microbiology