The central clock suffices to drive the majority of circulatory metabolic rhythms
P. Petrus, J. G. Smith, K. B. Koronowski, S. Chen, T. Sato, C. M. Greco, T. Mortimer, P.-S. Welz, V. M. Zinna, K. Shimaji, M. Cervantes, P. Baldi, P. M. Canoves, P. Sassone-Corsi, S. A. Benitah
The study shows that the central clock, via Syt10-expressing neurons, drives most circulatory metabolic rhythms and rescues glucose intolerance, highlighting its role in circadian communication.
bioRxiv · Jan 24, 2022Physiology