P. M. Kane

Human V-ATPase a-subunit isoforms bind specifically to distinct phosphoinositide phospholipids

The paper shows human V-ATPase a-subunit isoforms bind specific phosphoinositide lipids, with mutations disrupting this binding and suggesting a mechanism for organelle-specific V-ATPase regulation.

Chimeric a-subunit isoforms generate functional yeast V-ATPases with altered regulatory properties in vitro and in vivo

This paper designs chimeric V-ATPase a-subunit isoforms in yeast, showing altered regulatory properties and stress adaptation in vitro and in vivo.