Author

P. M. Zygmunt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Assay:electrophysiology· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

L. Moparthi· 3 shared J. Wenger· 1 shared M. Filipovic· 1 shared S. B. Moparthi· 1 shared V. Sinica· 1 shared V. Vlachova· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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3 shared papersPhysiology

L. Moparthi

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3 papers

Recent·Most cited

The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain

L. Moparthi, V. Sinica, M. Filipovic, V. Vlachova, P. M. Zygmunt

This paper investigates the temperature sensitivity of hTRPA1 by analyzing truncated proteins, finding that cold and heat sensitivity involve distinct structural changes in the C-terminal domain.

bioRxiv · Jul 31, 2021Physiology

Calcium activates purified human TRPA1 with and without its N-terminal ankyrin repeat domain in the absence of calmodulin

L. Moparthi, S. B. Moparthi, J. Wenger, P. M. Zygmunt

bioRxiv · Mar 19, 2020Physiology

Human TRPA1 is an inherently mechanosensitive bilayer-gated ion channel

P. M. Zygmunt, L. Moparthi

This study shows that human TRPA1 is a mechanosensitive ion channel gated by bilayer pressure, with responses modulated by redox state.

bioRxiv · Mar 5, 2020Physiology