PDL1 AND ICOSL DISCRIMINATE HUMAN SECRETORY AND HELPER DENDRITIC CELLS
C. Hoffmann, F. Noel, M. Grandclaudon, P. Michea, A. Surun, L. Faucheux, P. Sirven, J. Rochefort, O. Lantz, J. Klijanienko, C. Lecerf, M. Kamal, C. Le Tourneau, M. Guillot-Delost, V. Soumelis
The paper identifies two functional states of human activated dendritic cells, secretory DC and helper DC, distinguished by PDL1 and ICOSL expression and their distinct cytokine profiles and T cell stimulation capacities.
bioRxiv · Aug 1, 2019 · PreprintImmunology