Author
V. Soumelis
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2022 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 25 mutual co-author links7 papers
Recent·Most cited
GM-CSF-activated human dendritic cells promote type1 T follicular helper cells (Tfh1) polarization in a CD40-dependent manner
S. Korniotis, M. Saichi, C. Trichot, C. Hoffmann, E. Amblard, A. Viguier, S. Grondin, F. Noel, H. Mattoo, V. Soumelis
This study shows GM-CSF-activated human dendritic cells drive Tfh1 differentiation via CD40-dependent mechanisms, with implications for infections like tuberculosis and COVID-19.
bioRxiv · Apr 28, 2022 · PreprintImmunology
Characterization and functional interrogation of SARS-CoV-2 RNA interactome
A. Labeau, A. Lefevre-Utile, L. Bonnet-Madin, L. Fery-Simonian, V. Soumelis, V. Lotteau, P.-O. Vidalain, A. Amara, L. Meertens
This study identifies 142 RNA-binding proteins interacting with SARS-CoV-2 RNA and finds many are proviral, offering potential drug targets for antiviral therapies.
bioRxiv · Mar 23, 2021Microbiology
Single cell RNA sequencing of blood antigen-presenting cells in severe Covid-19 reveals multi-process defects in antiviral immunity
M. Saichi, M. Z. Ladjemi, S. Korniotis, C. Rousseau, Z. Ait-Hamou, L. Massenet, E. Amblard, F. Noel, Y. Marie, D. Bouteiller, J. Medvedovic, F. Pene, V. Soumelis
This study uses single-cell RNA sequencing to analyze blood antigen-presenting cells in severe COVID-19 patients, identifying defects in antiviral immunity.
bioRxiv · Jul 20, 2020Immunology
SARS-CoV-2 induces human plasmacytoid pre-dendritic cell diversification via UNC93B and IRAK4
F. Onodi, L. Bonnet-Madin, L. Meertens, L. Karpf, J. Poirot, S.-Y. Zhang, c. picard, A. Puel, E. Jouanguy, Q. Zhang, J. LeGoff, J.-M. Molina, C. Delaugerre, J.-L. Casanova, A. AMARA, V. Soumelis
This study shows SARS-CoV-2 activates human plasmacytoid pre-dendritic cells (pDC) via UNC93B and IRAK4, leading to interferon and cytokine production.
bioRxiv · Jul 10, 2020Immunology
MMP2 As An Independent Prognostic Stratifier In Oral Cavity Cancers
C. Hoffmann, S. Vacher, P. Sirven, C. Lecerf, L. Massenet, A. Moreira, A. Surun, A. Schnitzler, J. Klijanienko, O. Mariani, E. Jeannot, N. Badois, M. Lesnik, O. Choussy, C. Le Tourneau, , V. Soumelis
The paper identifies MMP2 as an independent prognostic biomarker for oral cavity cancers, associated with poor disease-specific survival.
bioRxiv · Aug 2, 2019Cancer Biology
PDL1 AND ICOSL DISCRIMINATE HUMAN SECRETORY AND HELPER DENDRITIC CELLS
C. Hoffmann, F. Noel, M. Grandclaudon, P. Michea, A. Surun, L. Faucheux, P. Sirven, J. Rochefort, O. Lantz, J. Klijanienko, C. Lecerf, M. Kamal, C. Le Tourneau, M. Guillot-Delost, V. Soumelis
The paper identifies two functional states of human activated dendritic cells, secretory DC and helper DC, distinguished by PDL1 and ICOSL expression and their distinct cytokine profiles and T cell stimulation capacities.
bioRxiv · Aug 1, 2019 · PreprintImmunology