Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases
M. Kaduri, M. Sela, S. Kagan, M. Poley, H. Abumanhal-Masarweh, P. Mora-Raimundo, A. Ouro, N. Dahan, J. Shklover, J. Shainsky-Roitman, Y. Buganim, A. Schroeder
This study shows that targeting neurons in breast cancer tumors with bupivacaine nanoparticles reduces cancer progression and metastases by inhibiting nerve-to-cancer signaling.
bioRxiv · May 18, 2021Cancer Biology