Author

Y. Buganim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

K. Makedonski· 2 shared R. Lasry· 2 shared A. Khatib· 1 shared A. Ouro· 1 shared A. Radwan· 1 shared A. Schroeder· 1 shared A. W. Cheng· 1 shared C. Ople· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

K. Makedonski

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fibroblasts-derived from Pluripotent Cells Harboring a Single Allele Knockout in Two Pluripotency Genes Exhibit DNA Methylation Abnormalities and pluripotency induction Defects

R. Lasry, N. Maoz, A. W. Cheng, N. Yom Tov, E. Kulenkampff, M. Azagury, H. Yang, C. Ople, S. Markoulaki, D. A. Faddah, K. Makedonski, O. Sabbag, R. Jaenisch, Y. Buganim

This study shows that fibroblasts from pluripotent cells with single-allele knockouts in two pluripotency genes have DNA methylation issues and reduced pluripotency induction ability.

bioRxiv · May 18, 2022 · PreprintCell Biology

Pluripotency-Independent Induction of Human Trophoblast Stem Cells from Fibroblasts

Y. Buganim, M. Naama, A. Radwan, V. Zayat, S. Sebban, M. Rahamim, R. Lasry, M. Jaber, O. Sabag, H. Yassen, D. Orzech, A. Khatib, S. Epsztejn-Litman, M. Novoselsky-Persky, K. Makedonski, , R. Eiges

This study identifies GOKM factors that can generate functional hiTSCs independently of pluripotency factors, showing distinct chromatin and gene expression profiles compared to OSKM-induced cells.

bioRxiv · Nov 10, 2021Cell Biology

Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases

M. Kaduri, M. Sela, S. Kagan, M. Poley, H. Abumanhal-Masarweh, P. Mora-Raimundo, A. Ouro, N. Dahan, J. Shklover, J. Shainsky-Roitman, Y. Buganim, A. Schroeder

This study shows that targeting neurons in breast cancer tumors with bupivacaine nanoparticles reduces cancer progression and metastases by inhibiting nerve-to-cancer signaling.

bioRxiv · May 18, 2021Cancer Biology