Intramolecular synergism and bacterial lysis regulation can explain the complex multi-domain architecture of the bacteriophage endolysin PlySK1249
F. Oechslin, C. Menzi, P. Moreillon, G. Resch
This study investigates the multi-domain architecture of PlySK1249, an endolysin from Streptococcus dysgalactiae phage, showing how its domains synergize for bacterial lysis and how proteolytic cleavage regulates this process.
bioRxiv · Dec 1, 2020Microbiology