G. Resch

Phage activity against Staphylococcus aureus is impaired in plasma and synovial fluid.

This study shows that anti-Staphylococcus aureus phages are highly inhibited in plasma and synovial fluid due to clot formation, which prevents bacterial lysis.

Subtherapeutic doses of vancomycin synergize with bacteriophages for treatment of experimental methicillin-resistant Staphylococcus aureus infective endocarditis

This study shows that combining subtherapeutic vancomycin with bacteriophages reduces MRSA bacterial load in experimental endocarditis.

Intramolecular synergism and bacterial lysis regulation can explain the complex multi-domain architecture of the bacteriophage endolysin PlySK1249

This study investigates the multi-domain architecture of PlySK1249, an endolysin from Streptococcus dysgalactiae phage, showing how its domains synergize for bacterial lysis and how proteolytic cleavage regulates this process.

Phage efficacy in infecting dual-strain biofilms of Pseudomonas aeruginosa

This study investigates how strain diversity in Pseudomonas aeruginosa biofilms affects phage efficacy, finding that spatial structure provides refuge and reduces resistance evolution.