Plasmodium falciparum Raf kinase inhibitor is a lipid binding protein that interacts with CDPK1 and regulates its activity in asexual blood stage.
M. Sharma, D. Krishnan, P. Negi, K. Rani, A. Revikumar, M. Munde, A. Bansal
This study identifies PfRKIP as a lipid-binding protein in Plasmodium falciparum that interacts with CDPK1, regulates its activity, and its inhibition reduces parasite growth.
bioRxiv · Aug 23, 2023 · PreprintBiochemistry