M. Munde

Plasmodium falciparum Raf kinase inhibitor is a lipid binding protein that interacts with CDPK1 and regulates its activity in asexual blood stage.

This study identifies PfRKIP as a lipid-binding protein in Plasmodium falciparum that interacts with CDPK1, regulates its activity, and its inhibition reduces parasite growth.

Interaction of 14-3-3I and CDPK1 mediates the growth of human malaria parasite

This study identifies 14-3-3I as a scaffold protein in Plasmodium falciparum and reveals its interaction with CDPK1, a key kinase, through phosphorylation-dependent binding, suggesting a potential target for antimalarial drug development.

Development of novel anti-malarial from structurally diverse library of molecules, targeting plant-like Calcium Dependent Protein Kinase 1, a multistage growth regulator of P. falciparum

The paper identifies a novel CDPK1 inhibitor from a molecular library that inhibits P. falciparum intra-erythrocytic growth in vitro.