Prefrontal allopregnanolone mediates the adverse effects of acute stress in a mouse model of tic pathophysiology
R. Cadeddu, M. Van Zandt, K. Odeh, C. J. Anderson, D. Flanagan, P. Nordkild, C. J. Pittenger, M. Bortolato
This study shows that allopregnanolone in the prefrontal cortex mediates stress-induced worsening of tics in a mouse model of Tourette syndrome.
bioRxiv · Oct 29, 2022Animal Behavior & Cognition