TRF1 prevents permissive DNA damage response, recombination and Break Induced Replication at telomeres
J.-B. Vannier, R. M. Porreca, P. P. Law, E. Herrera-Moyano, R. Gonzalez Franco, A. Montoya, P. Faull, H. Kramer
This study shows TRF1 prevents DNA damage response, recombination, and break-induced replication at telomeres by suppressing PML, BRCA1, and SMC5/6 complex accumulation.
bioRxiv · Jul 10, 2019 · PreprintCell Biology