P. Faull

m6A reader Pho92 is recruited co-transcriptionally and couples translation efficacy to mRNA decay to promote meiotic fitness in yeast

Engineering transplantable jejunal mucosal grafts using primary patient-derived organoids from children with intestinal failure

This study develops a method to create transplantable jejunal mucosal grafts using patient-derived organoids and decellularized scaffolds, demonstrating functional grafts in vitro and in vivo.

Proteasome-mediated protein degradation resets the cell division cycle and triggers ESCRT-III-mediated cytokinesis in an archaeon

This study identifies proteasome-mediated degradation of CdvB as a mechanism resetting the cell division cycle and triggering cytokinesis in the archaeon Sulfolobus acidocaldarius.

TRF1 prevents permissive DNA damage response, recombination and Break Induced Replication at telomeres

This study shows TRF1 prevents DNA damage response, recombination, and break-induced replication at telomeres by suppressing PML, BRCA1, and SMC5/6 complex accumulation.