Author

P. R. Soon-Shiong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

G. Nelson· 1 shared K. Niazi· 1 shared O. Buzko· 1 shared P. R. Spilman· 1 shared S. Rabizadeh· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

G. Nelson

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BiophysicsbioRxivPreprintJan 13, 2021

Molecular dynamic simulation reveals E484K mutation enhances spike RBD-ACE2 affinity and the combination of E484K, K417N and N501Y mutations (501Y.V2 variant) induces conformational change greater than N501Y mutant alone, potentially resulting in an escape mutant

G. Nelson, O. Buzko, P. R. Spilman…·P. R. Soon-Shiong

This study uses molecular dynamics simulations to show that the E484K mutation increases spike RBD-ACE2 affinity and that the combination of E484K, K417N, and N501Y mutations causes greater conformational changes, potentially leading to antibody escape.

DOI 10.1101/2021.01.13.426558

humanprotein structure

𝕏 PostBluesky