Structural maturation of SYCP1-mediated meiotic chromosome synapsis through conformational remodelling by molecular adapter SYCE3
J. H. Crichton, J. M. Dunce, O. M. Dunne, L. J. Salmon, P. S. Devenney, J. Lawson, I. R. Adams, O. R. Davies
The paper reveals that SYCE3 remodels the SYCP1 lattice during meiotic synapsis, enabling long-range synapsis by forming an integrated SYCP1-SYCE3 lattice.
bioRxiv · Mar 6, 2022 · PreprintBiochemistry