Author

J. H. Crichton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

I. R. Adams· 3 shared J. M. Dunce· 2 shared O. R. Davies· 2 shared J. Lawson· 1 shared L. J. Salmon· 1 shared O. M. Dunne· 1 shared P. S. Devenney· 1 shared W. M. Baarends· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

I. R. Adams

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Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 15, 2023

Computational Tools for the Analysis of Meiotic Prophase I Images

J. H. Crichton, I. R. Adams

The paper introduces computational tools for automated quantitative analysis of meiotic prophase I images, focusing on chromosome axis and recombination focus measurements.

DOI 10.1101/2023.11.15.567191

fluorescence / live-cell microscopydeep learning

𝕏 PostBluesky

Cell BiologybioRxivPreprintApr 14, 2022

Parallel recruitment pathways contribute to synaptonemal complex assembly during mammalian meiosis

J. H. Crichton, J. M. Dunce, W. M. Baarends…·I. R. Adams

This study shows that SYCE2 is recruited to recombination sites early in SC assembly, independent of SYCP1, suggesting parallel recruitment pathways in mammalian meiosis.

DOI 10.1101/2022.04.14.488335

mouseimaging

𝕏 PostBluesky

BiochemistrybioRxivPreprintMar 6, 2022

Structural maturation of SYCP1-mediated meiotic chromosome synapsis through conformational remodelling by molecular adapter SYCE3

J. H. Crichton, J. M. Dunce, O. M. Dunne…·O. R. Davies

The paper reveals that SYCE3 remodels the SYCP1 lattice during meiotic synapsis, enabling long-range synapsis by forming an integrated SYCP1-SYCE3 lattice.

DOI 10.1101/2022.03.06.483192

mouseexperimental assay

𝕏 PostBluesky