Application of high-throughput, high-depth, targeted single-nucleus DNA sequencing in pancreatic cancer
H. Zhang, E.-R. Karnoub, S. Umeda, R. Chaligne, I. Masilionis, C. A. McIntyre, A. Hayashi, P. Sashittal, A. Zucker, K. Mullen, A. Makohon-Moore, C. A. Iacobuzio-Donahue
This study develops a scalable workflow for targeted single-nucleus DNA sequencing in pancreatic cancer, enabling high-resolution genomic analysis of tumor subclones and normal cells.
bioRxiv · Mar 6, 2022Cancer Biology