Author

A. Makohon-Moore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

C. A. Iacobuzio-Donahue· 3 shared E. Papaemmanuil· 2 shared G. Gundem· 2 shared K. Mullen· 2 shared M. Levine· 2 shared A. Dogan· 1 shared A. Hayashi· 1 shared A. L. Kung· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

C. A. Iacobuzio-Donahue

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3 papers

Recent·Most cited

Subclonal somatic copy number alterations emerge and dominate in recurrent osteosarcoma

M. D. Kinnaman, S. Zaccaria, A. Makohon-Moore, B. Arnold, M. Levine, G. Gundem, J. E. A. Ossa, D. Glodzik, M. I. R. Sanchez, N. Bouvier, S. Li, E. Stockfisch, M. Dunigan, C. Cobbs, U. Bhanot, , C. A. Iacobuzio-Donahue

This study identifies subclonal copy number alterations in relapsed osteosarcoma, showing MYC gain/amplification in treatment-resistant clones and their emergence before chemotherapy.

bioRxiv · Jan 5, 2023 · PreprintCancer Biology

Application of high-throughput, high-depth, targeted single-nucleus DNA sequencing in pancreatic cancer

H. Zhang, E.-R. Karnoub, S. Umeda, R. Chaligne, I. Masilionis, C. A. McIntyre, A. Hayashi, P. Sashittal, A. Zucker, K. Mullen, A. Makohon-Moore, C. A. Iacobuzio-Donahue

This study develops a scalable workflow for targeted single-nucleus DNA sequencing in pancreatic cancer, enabling high-resolution genomic analysis of tumor subclones and normal cells.

bioRxiv · Mar 6, 2022Cancer Biology

Accelerated single cell seeding in relapsed multiple myeloma

H. J. Landau, V. Yellapantula, B. J. Diamond, E. H. Rustad, K. Maclachlan, G. Gundem, J. Medina-Martinez, J. E. Arango Ossa, M. Levine, Y. Zhou, K. L. Rajya, P. Baez, M. Attiyeh, A. Makohon-Moore, L. Zhang, , F. Maura

This study uses whole genome sequencing to show that relapsed multiple myeloma exhibits accelerated systemic seeding driven by chemotherapy-induced mutations and clonal expansion of single myeloma cells.

bioRxiv · Feb 25, 2020Cancer Biology