Distinct cell adhesion signature defines glioblastoma myeloid-derived suppressor cell subsets
D. Bayik, C. F. Bartels, K. Lovrenert, D. Watson, D. Zhang, K. Kay, A. Lauko, S. Johnson, A. Lo, M. McGraw, M. Grabowski, A. M. Mohammadi, F. Veglia, Y. Fan, M. A. Vogelbaum, , J. Lathia
The paper identifies distinct cell adhesion signatures in glioblastoma myeloid-derived suppressor cell subsets, showing that monocytic MDSCs drive tumor growth through enhanced integrin β1 expression.
bioRxiv · Sep 27, 2021Immunology