Author

A. Saiakhova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. R. Morton· 1 shared A. Vingiani· 1 shared B. Gyorffy· 1 shared C. Coombes· 1 shared C. F. Bartels· 1 shared C. Palmieri· 1 shared D. Hadjiminas· 1 shared D. N. Wald· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. R. Morton

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Author profile →

2 papers

Recent·Most cited

Mismatch-repair signature mutations activate gene enhancers across colorectal cancer epigenomes

S. Hung, A. Saiakhova, Z. Faber, C. F. Bartels, D. Neu, I. Bayles, E. Ojo, E. S. Hong, W. D. Pontius, A. R. Morton, R. Liu, M. F. Kalady, D. N. Wald, S. Markowitz, P. C. Scacheri

The paper identifies MMR signature mutations in colorectal cancer that activate enhancers by increasing FOX factor affinity and promoting tumor growth.

bioRxiv · Sep 7, 2018Cancer Biology

Enhancers mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer.

D. Patten, G. Corleone, B. Gyorffy, E. Erdos, A. Saiakhova, K. Goddard, A. Vingiani, S. Shousha, L. S. Pongor, D. Hadjiminas, G. Schiavon, P. Barry, C. Palmieri, C. Coombes, P. Scacheri, , L. Magnani

This study maps enhancers in luminal breast cancer to reveal phenotypic heterogeneity and its evolutionary dynamics during treatment.

bioRxiv · Sep 26, 2017Cancer Biology