Diminazene resistance in Trypanosoma congolense is linked to reduced mitochondrial membrane potential and not to reduced transport capacity
H. De Koning, L. V. Carruthers, J. C. Munday, G. U. Ebiloma, P. Steketee, S. Jayaraman, G. D. Campagnaro, M. A. Ungogo, A.-M. Donachie, T. G. Rowan, R. Peter, L. J. Morrison, M. P. Barrett
This study investigates diminazene resistance in Trypanosoma congolense and finds that resistance is due to reduced mitochondrial membrane potential rather than reduced drug transport capacity.
bioRxiv · Jul 28, 2020Microbiology