Prorenin from renal tubules is a major driver of diabetic kidney disease
A. Federlein, C. Lehrmann, P. Tauber, V. T. Todorov, F. Schweda
This study shows that prorenin from renal tubules drives diabetic kidney disease, explaining the paradox of increased prorenin and stable active renin in diabetes.
bioRxiv · Sep 26, 2022 · PreprintPhysiology