Cancer BiologybioRxiv
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts
Y. A. Yabo, P. M. Moreno-Sanchez, Y. Pires-Afonso…·A. Golebiewska
This study characterizes the tumor microenvironment in glioblastoma patient-derived xenografts and patient tumors, revealing phenotypic heterogeneity in microglia and their functional adaptations.