Author

A. Skupin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Oudin· 3 shared A. Golebiewska· 2 shared A. Michelucci· 2 shared A. Muller· 2 shared B. Klink· 2 shared F. Hertel· 2 shared K. Grzyb· 2 shared M. Mittelbronn· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Oudin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mechanism-based classification of SARS-CoV-2 Variants by Molecular Dynamics Resembles Phylogenetic Tree

T. Arns, A. Fouquier dHerouel, P. May, A. Tkatchenko, A. Skupin

This paper introduces a Persistence Score to classify SARS-CoV-2 variants based on molecular dynamics, showing it groups variants into clinically relevant subgroups with higher sensitivity than traditional methods.

bioRxiv · Nov 28, 2023 · PreprintBioinformatics

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts

Y. A. Yabo, P. M. Moreno-Sanchez, Y. Pires-Afonso, T. Kaoma, B. Nosirov, A. Scafidi, L. Ermini, A. Lipsa, A. Oudin, D. Kyriakis, K. Grzyb, S. K. Poovathingal, A. Poli, A. Muller, R. Toth, , A. Golebiewska

This study characterizes the tumor microenvironment in glioblastoma patient-derived xenografts and patient tumors, revealing phenotypic heterogeneity in microglia and their functional adaptations.

bioRxiv · Mar 5, 2023Cancer Biology

Formate Promotes Invasion and Metastasis by Activating Fatty Acid Synthesis and Matrix Metalloproteinases

C. Delbrouck, N. Kiweler, V. Pozdeev, L. Neises, A. Oudin, A. Schuster, A. F. D'Herouel, R. Shen, R. Halder, A. Lesur, C. Ogris, N. Lorenz, C. Jaeger, M. Ronellenfitsch, M. Piraud, , J. Meiser

bioRxiv · Jan 23, 2023 · PreprintCancer Biology

Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine

A. Golebiewska, A.-C. Hau, A. Oudin, D. Stieber, Y. A. Yabo, V. Baus, V. Barthelemy, E. Klein, S. Bougnaud, O. Keunen, M. Wantz, A. Michelucci, V. Neirinckx, A. Muller, T. Kaoma, , S. P. Niclou

This study shows that glioma PDOX models accurately represent patient tumors and can predict treatment responses in personalized medicine.

bioRxiv · Apr 24, 2020Cancer Biology

Mitochondrial morphology provides a mechanism for energy buffering at synapses

G. C. Garcia, T. M. Bartol, S. Phan, E. A. Bushong, G. Perkins, T. J. Sejnowski, M. H. Ellisman, A. Skupin

The paper presents an agent-based model of mitochondrial morphology at synapses, showing that internal structure influences energy buffering and cellular robustness.

bioRxiv · May 20, 2019Biophysics