Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins
L. Qin, F. Ben Bdira, Y. G. J. Sterckx, A. N. Volkov, J. Vreede, G. Giachin, P. van Schaik, M. Ubbink, R. T. Dame
This study identifies the molecular mechanism by which H-NS proteins switch DNA binding states in response to osmotic changes, showing that ionic strength affects electrostatic interactions between domains.
bioRxiv · Sep 5, 2019Biochemistry