Bacterial cGAS-like enzymes produce 2',3'-cGAMP to activate an ion channel that restricts phage replication
U. Tak, P. Walth, A. T. Whiteley
This study identifies bacterial CD-NTases that produce 2',3'-cGAMP to restrict phage replication by activating a chloride-selective ion channel.
bioRxiv · Jul 24, 2023Microbiology