P. Wijesinghe

Multimodal mechano-microscopy reveals mechanical phenotypes of breast cancer spheroids in three dimensions

This study uses multimodal mechano-microscopy to analyze mechanical properties of breast cancer spheroids in 3D environments, revealing differences in elasticity and invasion behavior between non-metastatic and metastatic spheroids.

UVA hyperspectral light-sheet microscopy for volumetric metabolic imaging: application to pre-implantation embryo development

This paper introduces a UVA hyperspectral light-sheet microscopy method to map metabolic activity in 3D, demonstrating its application to pre-implantation embryo development.

Experimentally unsupervised deconvolution for light-sheet microscopy with propagation-invariant beams

This paper introduces a deep learning deconvolution method for light-sheet microscopy using propagation-invariant beams, trained with physics-based images and unpaired data, achieving improved image contrast without requiring extensive paired training data.

Adult porcine (Sus scrofa) derived inner ear cells possessing multipotent stem/progenitor cell characteristics in in vitro cultures

This study reports the successful in vitro culture of adult porcine inner ear cells that retain stem/progenitor cell characteristics, offering a model for studying human inner ear disorders.

Widefield light sheet microscopy using an Airy beam combined with deep-learning super-resolution

This paper introduces a method combining an Airy beam and deep-learning super-resolution to enhance resolution and field of view in light-sheet microscopy, demonstrating improvements in imaging biological samples.

Molecular phylogeny of wood decay fungi of hardwood and their ability to produce laccase that correlates with triphenylmethane dye decolorization

The paper identifies fungal species from decaying hardwood in Sri Lanka and finds a significant correlation between laccase production and triphenylmethane dye decolorization.