Author

S. E. Amos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Mowla· 3 shared B. F. Kennedy· 3 shared Y. S. Choi· 3 shared D. Vahala· 2 shared J. Li· 2 shared M. S. Hepburn· 2 shared A. A. Oberai· 1 shared A. Saxena· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBioengineering

A. Mowla

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multimodal mechano-microscopy reveals mechanical phenotypes of breast cancer spheroids in three dimensions

A. Mowla, M. S. Hepburn, J. Li, D. Vahala, S. E. Amos, L. M. Hirvonen, R. W. Sanderson, P. Wijesinghe, S. Maher, Y. S. Choi, B. F. Kennedy

This study uses multimodal mechano-microscopy to analyze mechanical properties of breast cancer spheroids in 3D environments, revealing differences in elasticity and invasion behavior between non-metastatic and metastatic spheroids.

APL Bioengineering · Sep 9, 2024Peer-reviewedBioengineering

Tumor spheroid elasticity estimation using mechano-microscopy combined with a conditional generative adversarial network

K. Y. Foo, B. Shaddy, J. Murgoitio-Esandi, M. S. Hepburn, J. Li, A. Mowla, D. Vahala, S. E. Amos, Y. S. Choi, A. A. Oberai, B. F. Kennedy

This study trains a conditional generative adversarial network to estimate tumor spheroid elasticity from phase difference images, showing improved robustness to noise compared to traditional methods.

bioRxiv · Apr 12, 2024Bioengineering

Polymer-mediated oligonucleotide delivery enables construction of barcoded 3D cultures for spatial single-cell analysis

J. J. King, A. Mowla, J. A. Kretzmann, M. Norret, U. D. Kadolsky, M. Iqbal, A. Saxena, S. S. A. Mamsa, S. E. Amos, Y. S. Choi, B. F. Kennedy, K. S. Iyer, N. M. Smith, C. W. Evans

The paper introduces a method to create barcoded 3D cell cultures for spatial single-cell analysis using polymer-mediated oligonucleotide delivery and multiplex single-cell RNA sequencing.

bioRxiv · Nov 20, 2023 · PreprintBioengineering