Author

P.-H. Puech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Sadoun· 2 shared K. Sengupta· 2 shared L. Limozin· 2 shared M. Biarnes-Pelicot· 2 shared Y. Hamon· 2 shared A. Babataheri· 1 shared A. Badache· 1 shared A. I. Barakat· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiophysics

A. Sadoun

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Probing mechanical interaction of immune receptors and cytoskeleton by membrane nanotube extraction

F. Manca, G. Eich, O. N'Dao, L. Normand, K. Sengupta, L. Limozin, P.-H. Puech

This study uses mechanical extraction and modeling to investigate the mechanical link between immune receptors and the cytoskeleton, revealing that TCR-complex and open LFA1 form such links.

bioRxiv · Sep 15, 2022Biophysics

Spatio-temporal Force Patterns Reveal a Mechanical Set Point in Early T Cell Activation

F. Mustapha, M. Biarnes-Pelicot, R. Torro, J. El Husseiny, K. Sengupta, P.-H. Puech

This study uses traction force microscopy to analyze early T cell force generation and identifies distinct mechanical response patterns in human T cells.

bioRxiv · Feb 11, 2022 · PreprintBiophysics

Controlling T cells shape, mechanics and activation by micropatterning.

A. Sadoun, M. Biarnes-Pelicot, L. Ghesquiere-Dierickx, A. Wu, O. Theodoly, L. Limozin, Y. Hamon, P.-H. Puech

This paper demonstrates a method to control T cell shape, mechanics, and activation using micropatterned substrates and shows that adhesion to aCD45 does not affect calcium fluxes.

bioRxiv · Sep 15, 2020 · PreprintBiophysics

iASPP contributes to cortex rigidity, astral microtubule capture and mitotic spindle positioning

A. Mangon, D. Salaün, M. Lala Bouali, S. Quitard, D. Isnardon, S. Audebert, P.-H. Puech, P. Verdier-Pinard, A. Badache

This study shows iASPP interacts with EB1 and Myo1c to regulate cortical rigidity, microtubule capture, and spindle positioning during mitosis.

bioRxiv · Dec 10, 2019Cell Biology

Single-cell immuno-mechanics: rapid viscoelastic changes are a hallmark of early leukocyte activation.

A. Zak, S. V. Merino-Cortes, A. Sadoun, A. Babataheri, S. Dogniaux, S. Dupre-Crochet, E. Hudik, H.-T. He, A. I. Barakat, Y. R. Carrasco, Y. Hamon, P.-H. Puech, C. Hivroz, O. Nüsse, J. Husson

This study shows that leukocytes become significantly stiffer and more viscous within seconds of contact with target cells, with mechanical properties evolving in parallel and maintaining a cell-type-specific ratio.

bioRxiv · Nov 22, 2019 · PreprintBiophysics