GeneticsbioRxivPreprint
Differential functions of upstream and intronic HOT regions shape dlg-1 transcription and C. elegans development
Cristina Tocchini, Fanny Eggeler, Palmer Bassett, Susan E. Mango
The paper identifies two HOT regions in the C. elegans dlg-1 gene, showing the upstream region is essential for transcription and development, while the intronic region modestly enhances transcription in epidermal cells.
DOI 10.1101/2025.06.13.659077