Author

Paola Carrillo Flores

The University of Texas Health Science Center at Houston

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Biochemistry· 1

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Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

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Vasanthi Jayaraman· 1 shared Vladimir Berka· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiochemistry

Vasanthi Jayaraman

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintDec 12, 2025

JNJ-55511118 Stabilizes a Desensitized-like Conformation of γ8-Containing AMPA Receptors through Long-Range Allosteric Modulation

Paola Carrillo Flores, Vladimir Berka, Vasanthi Jayaraman

This study shows JNJ-118 stabilizes a desensitized-like conformation of γ8-containing AMPA receptors through long-range allosteric modulation without disrupting the AMPAR-γ8 complex.

DOI 10.64898/2025.12.10.693459

electrophysiologyexperimental assay

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