Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
María J. Conde-Dusman, Partha N. Dey, Oscar Elía-Zudaire, Luis G. Rabaneda, Carmen García-Lira, Teddy Grand, Víctor Briz, Eric Raúl Velasco, Raül Andero, Sergio Niñerola, Ángel Barco, Pierre Paoletti, John F. Wesseling, Fabrizio Gardoni, Steven J. Tavalin, Isabel Pérez-Otaño
This study identifies GluN3A-NMDA receptors as negative regulators of GIT1/mTORC1 assembly, showing their role in controlling synaptic protein synthesis and memory formation.
eLife · Nov 17, 2021Peer-reviewedNeuroscience