ZDHHC17-Mediated Palmitoylation of Hepatitis E Virus ORF3 Protein Regulates Vectorial Trafficking in Polarized Epithelial Cells
Patrick Broescky, Charlotte Caroline Syren, Di Ge, Leonid Kostrykin, Antonio Piras, Zoé Engels, Andrew Freistaedter, Huanting Chi, Paula Jordan, Charlotta Funaya, K Rohr, Sandhya P. Tiwari, Thibault Tubiana, Andreas Pichlmair, Viet Loan Dao Thi
This study identifies ZDHHC17-mediated palmitoylation of HEV ORF3 protein as critical for directional secretion in polarized epithelial cells.
bioRxiv · Jun 18, 2026 · PreprintCell Biology