Hijacking a bacterial membrane transporter for efficient genetic code expansion
Tarun Iype, Maximilian Fottner, Paul Böhm, Carlos Piedrafita, Kathrin Lang
This paper improves genetic code expansion by engineering a bacterial transporter to enhance non-canonical amino acid uptake, enabling efficient incorporation of multiple ncAAs into proteins.
bioRxiv · Mar 6, 2025 · PreprintSynthetic Biology