Author

Carlos Piedrafita

MRC Laboratory of Molecular BiologyORCID 0000-0002-1788-2033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

A. D. DicksoniD· 1 shared Caroline WeberiD· 1 shared Daniel L. DunkelmanniD· 1 shared Daniel RichteriD· 1 shared Fan Zhang· 1 shared Jason W. ChiniD· 1 shared Kathrin LangiD· 1 shared Kim C. LiuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

A. D. DicksonORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintApr 17, 2026

Expanding the genetic code with diverse backbone structures across diverse sequence contexts

Carlos Piedrafita, A. D. Dickson, Daniel Richter…·Jason W. Chin

This paper expands the genetic code by incorporating non-canonical monomers into proteins using evolved tRNAs and orthogonal synthetases, enabling broader sequence context compatibility.

2 citations

experimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 6, 2025

Hijacking a bacterial membrane transporter for efficient genetic code expansion

Tarun Iype, Maximilian Fottner, Paul Böhm…·Kathrin Lang

This paper improves genetic code expansion by engineering a bacterial transporter to enhance non-canonical amino acid uptake, enabling efficient incorporation of multiple ncAAs into proteins.

3 citations

bacteria (other)experimental assay

𝕏 PostBluesky