Construction of an MRCUT1 Cutinase-Expressing Saccharomyces boulardii Probiotic Yeast Strain Capable of Degrading Polyethylene Terephthalate (PET) Microplastics
Luisa Marie S. Jingco, Albert Derrick R. Recio, Addie Franchesca D. Manrique, Daniel Jericho H. Dungo, Paul Cedric Bernardo, Gabriel Mendoza-Rojas, Raphael Mosquito, Lexi Caitlin Murillo, Joe Anthony Manzano, Nicanor Pier Giorgio Austriaco
This paper genetically engineers Saccharomyces boulardii to express MRCUT1 cutinase, enabling PET microplastic degradation in vitro, with significant weight loss observed within a week.
bioRxiv · Jul 16, 2025 · PreprintMicrobiology