Developmentally-regulated splice remodeling shapes functional CACNA1C channel diversity during human neurodevelopment
Melis Celik, Osama A. Arshad, Nicola A.L. Hall, Sumeyye Suheda Yasarbas, Mahnaz Nikpour, Lina Jonsson, Carl M. Sellgren, Mikael Landen, Antonios Pantazis, Paul J. Harrison, Arne W. Mould, Erik Smedler
This study identifies developmentally-regulated alternative splicing of CACNA1C during human neurodevelopment and shows it affects CaV1.2 channel function.
bioRxiv · Nov 9, 2026 · PreprintDevelopmental Biology