Author

Paul J. Hoover

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

Alice HorisbergeriD· 2 shared Andrea FavaiD· 2 shared Anne DavidsoniD· 2 shared Arnon AraziiD· 2 shared Betty DiamondiD· 2 shared Carla Marie CudaiD· 2 shared Céline C. BerthieriD· 2 shared Chaim PuttermaniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Alice HorisbergerORCID

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2 papers

Recent·Most cited

Early and late RNA eQTL are driven by different genetic mechanisms

Saori Sakaue, Accelerating Medicines Partnership®: RA/SLE Network, Jennifer H. Anolik, William Apruzzese, Arnon Arazi, Jennifer L. Barnas, H. Michael Belmont, Céline C. Berthier, Jill P. Buyon, Michelle Curtis, Carla Marie Cuda, Maria Dall’Era, Anne Davidson, Betty Diamond, Thomas Eisenhaure, , Soumya Raychaudhuri

The paper identifies distinct genetic mechanisms for early (nuclear) and late (cellular) RNA eQTL by comparing their genomic localization and functional effects across tissues.

Nature Communications · Apr 25, 2026Peer-reviewedGenomics

A population-scale atlas of blood and tissue in lupus nephritis

Nicholas W. Sugiarto, Siddarth Gurajala, Michelle L. Curtis, Thomas Eisenhaure, Arnon Arazi, Andrea Fava, Qian Xiao, Joseph Mears, Brad H. Rovin, Céline C. Berthier, Yu Zhao, Peter Izmirly, Jennifer L. Barnas, Paul J. Hoover, Michael Peters, , Soumya Raychaudhuri

A single-cell atlas of blood and tissue samples from lupus nephritis patients and healthy controls identifies stromal and immune populations, including scar-associated macrophages, which correlate with disease activity.

bioRxiv · Aug 11, 2025 · PreprintMolecular Biology