Carla Marie Cuda

The paper identifies four distinct synovial macrophage populations in RA models and shows conserved inflammatory responses across conditions.

The paper identifies distinct genetic mechanisms for early (nuclear) and late (cellular) RNA eQTL by comparing their genomic localization and functional effects across tissues.

The paper identifies immune cell populations and gene expression differences associated with non-inflammatory pain in RA patients using flow cytometry and single-cell RNA-seq.

A single-cell atlas of blood and tissue samples from lupus nephritis patients and healthy controls identifies stromal and immune populations, including scar-associated macrophages, which correlate with disease activity.

The paper identifies profibrotic monocyte-derived alveolar macrophages as a biomarker and therapeutic target in SSc-ILD by analyzing BAL fluid and lung explants.

The paper identifies three subpopulations of tissue-resident monocyte-lineage cells in inflammatory arthritis and examines their origins and responses to synovial disruption.

The paper identifies activated lymphocyte phenotypes in individuals at risk for rheumatoid arthritis using mass cytometry and develops an immunophenotype score to distinguish these individuals from controls.

This study presents lineage tracing results from 18 myeloid-specific fate-mapping models in mouse peripheral blood and synovial tissue, validating synovial macrophage identification through flow cytometry and CITE-seq.

This study identifies distinct TNF-dependent aging signatures in monocyte subpopulations, showing that aging affects their transcriptional regulation differently.

This study identifies three monocyte transcriptional subgroups in SSc patients that correlate with disease activity, particularly lung function.

This study shows that monocyte depletion reduces ventricle enlargement and preserves white matter integrity after traumatic brain injury, suggesting it as a potential therapeutic strategy.