Author

Paul K. Spearing

Vanderbilt University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1

Frequent Co-Authors

Alice L. RodrigueziD· 1 shared Colleen Marie NiswenderiD· 1 shared Jonathan A. JavitchiD· 1 shared Justin B. SteinfeldiD· 1 shared Madeline Laramee· 1 shared Wesley B. AsheriD· 1 shared Xia LeiiD· 1 shared Xin LiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Alice L. RodriguezORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Transmembrane Domain Dominance Drives Emergent Signaling and Allosteric Inversion in mGlu1/5 Heterodimers

Justin B. Steinfeld, Xia Lei, Madeline Laramee, Xin Lin, Alice L. Rodriguez, Paul K. Spearing, Wesley B. Asher, Colleen Marie Niswender, Jonathan A. Javitch

The paper shows that signaling in mGlu1/5 heterodimers is dominated by the mGlu protomer, leading to emergent signaling and allosteric inversion, with implications for drug design.

bioRxiv · May 22, 2026 · PreprintNeuroscience