Single-cell intracellular epitope and transcript detection revealing signal transduction dynamics
Francesca Rivello, Erik van Buijtenen, Kinga Matuła, Jessie A.G.L. van Buggenum, Paul M. Vink, Hans van Eenennaam, Klaas W. Mulder, Wilhelm T. S. Huck
This paper introduces QuRIE-seq to simultaneously measure RNA and intracellular epitopes, demonstrating its ability to track B-cell receptor pathway activation and drug response over time.
Cell Reports Methods · Sep 1, 2021Peer-reviewedMolecular Biology